Multi-Scale Biomechanical Remodeling in Aging and Genetic Mutant Murine Mitral Valve Leaflets: Insights into Marfan Syndrome

Open Access

Peer-reviewed

Research Article

Russell A. Gould,

Affiliation Department of Biomedical Engineering, Cornell University, Ithaca, New York, United States of America
⨯
Ravi Sinha,

Affiliation Department of Biomedical Engineering, Cornell University, Ithaca, New York, United States of America
⨯
Hamza Aziz,

Affiliation Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Rosanne Rouf,

Affiliation Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Harry C. Dietz III,

Affiliations Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Howard Hughes Medical Institute, Bethesda, Maryland, United States of America
⨯
Daniel P. Judge,

Affiliation Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Jonathan Butcher

* E-mail: jtb47@cornell.edu

Affiliation Department of Biomedical Engineering, Cornell University, Ithaca, New York, United States of America
⨯

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Biomechanics
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Cell biology
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Extracellular matrix
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Mouse models
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Stiffness
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Confocal microscopy
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