Protective Efficacy of Newcastle Disease Virus Expressing Soluble Trimeric Hemagglutinin against Highly Pathogenic H5N1 Influenza in Chickens and Mice

Lisette A. H. M. Cornelissen; Olav S. de Leeuw; Mirriam G. Tacken; Heleen C. Klos; Robert P. de Vries; Els A. de Boer-Luijtze; Diana J. van Zoelen-Bos; Alan Rigter; Peter J. M. Rottier; Rob J. M. Moormann; Cornelis A. M. de Haan

doi:10.1371/journal.pone.0044447

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Open Access

Peer-reviewed

Research Article

Protective Efficacy of Newcastle Disease Virus Expressing Soluble Trimeric Hemagglutinin against Highly Pathogenic H5N1 Influenza in Chickens and Mice

Lisette A. H. M. Cornelissen ,

* E-mail: lisette.cornelissen@wur.nl

Affiliation Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands
⨯
Olav S. de Leeuw,

Affiliation Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands
⨯
Mirriam G. Tacken,

Affiliation Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands
⨯
Heleen C. Klos,

Affiliation Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands
⨯
Robert P. de Vries,

Affiliation Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Els A. de Boer-Luijtze,

Affiliation Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands
⨯
Diana J. van Zoelen-Bos,

Affiliation Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands
⨯
Alan Rigter,

Affiliation Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Peter J. M. Rottier,

Affiliation Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Rob J. M. Moormann,

Affiliations Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands, Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯
Cornelis A. M. de Haan

Affiliation Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
⨯

Protective Efficacy of Newcastle Disease Virus Expressing Soluble Trimeric Hemagglutinin against Highly Pathogenic H5N1 Influenza in Chickens and Mice

Lisette A. H. M. Cornelissen,
Olav S. de Leeuw,
Mirriam G. Tacken,
Heleen C. Klos,
Robert P. de Vries,
Els A. de Boer-Luijtze,
Diana J. van Zoelen-Bos,
Alan Rigter,
Peter J. M. Rottier,
Rob J. M. Moormann

Published: August 28, 2012
https://doi.org/10.1371/journal.pone.0044447

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