Galectin-8 Promotes Cytoskeletal Rearrangement in Trabecular Meshwork Cells through Activation of Rho Signaling

Shiri Diskin; Wei-Sheng Chen; Zhiyi Cao; Smita Gyawali; Haiyan Gong; Andrea Soza; Alfonso González; Noorjahan Panjwani

doi:10.1371/journal.pone.0044400

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Peer-reviewed

Research Article

Galectin-8 Promotes Cytoskeletal Rearrangement in Trabecular Meshwork Cells through Activation of Rho Signaling

Shiri Diskin ,

Contributed equally to this work with: Shiri Diskin, Wei-Sheng Chen

Affiliation Program in Cell, Molecular & Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, United States of America
⨯
Wei-Sheng Chen ,

Contributed equally to this work with: Shiri Diskin, Wei-Sheng Chen

Affiliation Program in Cell, Molecular & Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, United States of America
⨯
Zhiyi Cao,

Affiliation New England Eye Center and Department of Ophthalmology, Tufts University, Boston, Massachusetts, United States of America
⨯
Smita Gyawali,

Affiliation New England Eye Center and Department of Ophthalmology, Tufts University, Boston, Massachusetts, United States of America
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Haiyan Gong,

Affiliation Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, United States of America
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Andrea Soza,

Affiliations Departamento de Inmunología Clínica y Reumatología, Facultad de Medicina, Centro de Regulación Celular y Patología and Centro de Envejecimiento y Regeneración, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile, Millennium Institute for Fundamental and Applied Biology, Santiago, Chile
⨯
Alfonso González,

Affiliations Departamento de Inmunología Clínica y Reumatología, Facultad de Medicina, Centro de Regulación Celular y Patología and Centro de Envejecimiento y Regeneración, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile, Millennium Institute for Fundamental and Applied Biology, Santiago, Chile
⨯
Noorjahan Panjwani

* E-mail: Noorjahan.Panjwani@tufts.edu

Affiliations Program in Cell, Molecular & Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, United States of America, New England Eye Center and Department of Ophthalmology, Tufts University, Boston, Massachusetts, United States of America, Department of Biochemistry, Tufts University, Boston, Massachusetts, United States of America
⨯

Galectin-8 Promotes Cytoskeletal Rearrangement in Trabecular Meshwork Cells through Activation of Rho Signaling

Shiri Diskin,
Wei-Sheng Chen,
Zhiyi Cao,
Smita Gyawali,
Haiyan Gong,
Andrea Soza,
Alfonso González,
Noorjahan Panjwani

Published: September 4, 2012
https://doi.org/10.1371/journal.pone.0044400

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Cytoskeleton
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Phosphorylation
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Integrins
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Cell staining
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Actins
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Cell adhesion
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