Human Endometrial Stromal Stem Cells Differentiate into Megakaryocytes with the Ability to Produce Functional Platelets

Jinju Wang; Shuzhen Chen; Cheng Zhang; Samantha Stegeman; Teresa Pfaff-Amesse; Ying Zhang; Wenfeng Zhang; Lawrence Amesse; Yanfang Chen

doi:10.1371/journal.pone.0044300

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Peer-reviewed

Research Article

Human Endometrial Stromal Stem Cells Differentiate into Megakaryocytes with the Ability to Produce Functional Platelets

Jinju Wang ,

Contributed equally to this work with: Jinju Wang, Shuzhen Chen

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America
⨯
Shuzhen Chen ,

Contributed equally to this work with: Jinju Wang, Shuzhen Chen

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America
⨯
Cheng Zhang,

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America
⨯
Samantha Stegeman,

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America
⨯
Teresa Pfaff-Amesse,

Affiliation Department of Obstetrics & Gynecology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America
⨯
Ying Zhang,

Affiliation Department of Obstetrics & Gynecology, Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, China
⨯
Wenfeng Zhang,

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America
⨯
Lawrence Amesse ,

¶These authors also contributed equally to this work.

Affiliation Department of Obstetrics & Gynecology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America
⨯
Yanfang Chen

* E-mail: yanfang.chen@wright.edu

¶These authors also contributed equally to this work.

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America
⨯

Human Endometrial Stromal Stem Cells Differentiate into Megakaryocytes with the Ability to Produce Functional Platelets

Jinju Wang,
Shuzhen Chen,
Cheng Zhang,
Samantha Stegeman,
Teresa Pfaff-Amesse,
Ying Zhang,
Wenfeng Zhang,
Lawrence Amesse,
Yanfang Chen

Published: August 31, 2012
https://doi.org/10.1371/journal.pone.0044300

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