Estimated Glomerular Filtration Rate Is a Poor Predictor of the Concentration of Middle Molecular Weight Uremic Solutes in Chronic Kidney Disease

Nathalie Neirynck; Sunny Eloot; Griet Glorieux; Daniela V. Barreto; Fellype C. Barreto; Sophie Liabeuf; Aurélie Lenglet; Horst D. Lemke; Ziad A. Massy; Raymond Vanholder

doi:10.1371/journal.pone.0044201

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Open Access

Peer-reviewed

Research Article

Estimated Glomerular Filtration Rate Is a Poor Predictor of the Concentration of Middle Molecular Weight Uremic Solutes in Chronic Kidney Disease

Nathalie Neirynck ,

Contributed equally to this work with: Nathalie Neirynck, Sunny Eloot

* E-mail: n.neirynck@ugent.be

Affiliation Nephrology Section, Department of Internal Medicine, Ghent University Hospital, Gent, Belgium
⨯
Sunny Eloot ,

Contributed equally to this work with: Nathalie Neirynck, Sunny Eloot

Affiliation Nephrology Section, Department of Internal Medicine, Ghent University Hospital, Gent, Belgium
⨯
Griet Glorieux,

Affiliation Nephrology Section, Department of Internal Medicine, Ghent University Hospital, Gent, Belgium
⨯
Daniela V. Barreto,

Affiliations INSERM U-1088, Amiens, France, Clinical Research Centre, Division of Clinical Pharmacology, Amiens University Hospital, Amiens, France, and the Jules Verne University of Picardy, Amiens, France
⨯
Fellype C. Barreto,

Affiliations INSERM U-1088, Amiens, France, Clinical Research Centre, Division of Clinical Pharmacology, Amiens University Hospital, Amiens, France, and the Jules Verne University of Picardy, Amiens, France
⨯
Sophie Liabeuf,

Affiliations INSERM U-1088, Amiens, France, Clinical Research Centre, Division of Clinical Pharmacology, Amiens University Hospital, Amiens, France, and the Jules Verne University of Picardy, Amiens, France
⨯
Aurélie Lenglet,

Affiliations INSERM U-1088, Amiens, France, Division of Nephrology, Amiens University Hospital, Amiens, France
⨯
Horst D. Lemke,

Affiliation EXcorLab GmbH, Obernburg, Germany
⨯
Ziad A. Massy,

Affiliations INSERM U-1088, Amiens, France, Clinical Research Centre, Division of Clinical Pharmacology, Amiens University Hospital, Amiens, France, and the Jules Verne University of Picardy, Amiens, France, Division of Nephrology, Amiens University Hospital, Amiens, France
⨯
Raymond Vanholder

Affiliation Nephrology Section, Department of Internal Medicine, Ghent University Hospital, Gent, Belgium
⨯

Estimated Glomerular Filtration Rate Is a Poor Predictor of the Concentration of Middle Molecular Weight Uremic Solutes in Chronic Kidney Disease

Nathalie Neirynck,
Sunny Eloot,
Griet Glorieux,
Daniela V. Barreto,
Fellype C. Barreto,
Sophie Liabeuf,
Aurélie Lenglet,
Horst D. Lemke,
Ziad A. Massy,
Raymond Vanholder

Published: August 31, 2012
https://doi.org/10.1371/journal.pone.0044201

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