Resveratrol Inhibits LPS-Induced MAPKs Activation via Activation of the Phosphatidylinositol 3-Kinase Pathway in Murine RAW 264.7 Macrophage Cells

Yi Zong; Lin Sun; Bin Liu; Yi-Shu Deng; Dong Zhan; Yuan-Li Chen; Ying He; Jing Liu; Zong-Ji Zhang; Jun Sun; Di Lu

doi:10.1371/journal.pone.0044107

Loading metrics

Open Access

Peer-reviewed

Research Article

Resveratrol Inhibits LPS-Induced MAPKs Activation via Activation of the Phosphatidylinositol 3-Kinase Pathway in Murine RAW 264.7 Macrophage Cells

Yi Zong ,

Contributed equally to this work with: Yi Zong, Lin Sun

Affiliation Department of Anatomy, Kunming Medical University, Kunming, Yunnan, People’s Republic of China
⨯
Lin Sun ,

Contributed equally to this work with: Yi Zong, Lin Sun

Affiliation Department of Cardiology, The Second Affiliated Hospital, Kunming Medical University, Kunming, Yunnan, People’s Republic of China
⨯
Bin Liu,

Affiliation Department of Spine Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China
⨯
Yi-Shu Deng,

Affiliation Department of Respiratory Medicine, The Third People’s of Yunnan Province, Kunming, Yunnan, People’s Republic of China
⨯
Dong Zhan,

Affiliation Department of Anatomy, Kunming Medical University, Kunming, Yunnan, People’s Republic of China
⨯
Yuan-Li Chen,

Affiliation Department of Anatomy, Kunming Medical University, Kunming, Yunnan, People’s Republic of China
⨯
Ying He,

Affiliation Department of Anatomy, Kunming Medical University, Kunming, Yunnan, People’s Republic of China
⨯
Jing Liu,

Affiliation Department of Pathology, Kunming Medical University, Kunming, Yunnan, People’s Republic of China
⨯
Zong-Ji Zhang ,

* E-mail: ludi20040609@126.com (DL); sunjun6661@126.com (JS); zhzji@sina.com (ZJZ)

Affiliation Department of Pathology, Kunming Medical University, Kunming, Yunnan, People’s Republic of China
⨯
Jun Sun ,

* E-mail: ludi20040609@126.com (DL); sunjun6661@126.com (JS); zhzji@sina.com (ZJZ)

Affiliation Department of Anatomy, Kunming Medical University, Kunming, Yunnan, People’s Republic of China
⨯
Di Lu

* E-mail: ludi20040609@126.com (DL); sunjun6661@126.com (JS); zhzji@sina.com (ZJZ)

Affiliation Department of Anatomy, Kunming Medical University, Kunming, Yunnan, People’s Republic of China
⨯

Resveratrol Inhibits LPS-Induced MAPKs Activation via Activation of the Phosphatidylinositol 3-Kinase Pathway in Murine RAW 264.7 Macrophage Cells

Yi Zong,
Lin Sun,
Bin Liu,
Yi-Shu Deng,
Dong Zhan,
Yuan-Li Chen,
Ying He,
Jing Liu,
Zong-Ji Zhang,
Jun Sun

Published: August 31, 2012
https://doi.org/10.1371/journal.pone.0044107

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Phosphorylation
Is the Subject Area "Phosphorylation" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
MAPK signaling cascades
Is the Subject Area "MAPK signaling cascades" applicable to this article?

Thanks for your feedback.
Inflammatory diseases
Is the Subject Area "Inflammatory diseases" applicable to this article?

Thanks for your feedback.
Signal inhibition
Is the Subject Area "Signal inhibition" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Protein kinase signaling cascade
Is the Subject Area "Protein kinase signaling cascade" applicable to this article?

Thanks for your feedback.