Ablation of Dihydroceramide Desaturase Confers Resistance to Etoposide-Induced Apoptosis In Vitro

Monowarul M. Siddique; Benjamin T. Bikman; Liping Wang; Li Ying; Erin Reinhardt; Guanghou Shui; Markus R. Wenk; Scott A. Summers

doi:10.1371/journal.pone.0044042

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Open Access

Peer-reviewed

Research Article

Ablation of Dihydroceramide Desaturase Confers Resistance to Etoposide-Induced Apoptosis In Vitro

Monowarul M. Siddique ,

* E-mail: scott.summers@duke-nus.edu.sg (SAS); mobin.siddique@duke-nus.edu.sg (MMS)

Affiliation Program in Cardiovascular and Metabolic Diseases, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore
⨯
Benjamin T. Bikman,

Affiliations Program in Cardiovascular and Metabolic Diseases, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore, Department of Physiology and Developmental Biology, Brigham Young University, Provo, Utah, United States of America
⨯
Liping Wang,

Affiliation Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Li Ying,

Affiliation Program in Cardiovascular and Metabolic Diseases, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore
⨯
Erin Reinhardt,

Affiliation Program in Cardiovascular and Metabolic Diseases, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore
⨯
Guanghou Shui,

Affiliation Department of Biochemistry, National University of Singapore, Singapore, Singapore
⨯
Markus R. Wenk,

Affiliation Department of Biochemistry, National University of Singapore, Singapore, Singapore
⨯
Scott A. Summers

* E-mail: scott.summers@duke-nus.edu.sg (SAS); mobin.siddique@duke-nus.edu.sg (MMS)

Affiliations Program in Cardiovascular and Metabolic Diseases, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore, Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯

Ablation of Dihydroceramide Desaturase Confers Resistance to Etoposide-Induced Apoptosis In Vitro

Monowarul M. Siddique,
Benjamin T. Bikman,
Liping Wang,
Li Ying,
Erin Reinhardt,
Guanghou Shui,
Markus R. Wenk,
Scott A. Summers

Published: September 11, 2012
https://doi.org/10.1371/journal.pone.0044042

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