Granzyme B-Induced Neurotoxicity Is Mediated via Activation of PAR-1 Receptor and Kv1.3 Channel

• Tongguang Wang,

  Affiliation Section of Infections of the Nervous System, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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• Myoung-Hwa Lee,

  Affiliation Section of Infections of the Nervous System, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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• Elliot Choi,

  Affiliation Section of Infections of the Nervous System, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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• Carlos A. Pardo-Villamizar,

  Affiliation Department of Neurology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Sung Bin Lee,

  Affiliation Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America

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• In Hong Yang,

  Affiliations Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America, Singapore Institute for Nanotechnology, National University of Singapore, Singapore, Singapore

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• Peter A. Calabresi,

  Affiliation Department of Neurology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Avindra Nath

  * E-mail: natha@ninds.nih.gov

  Affiliations Department of Neurology, Johns Hopkins University, Baltimore, Maryland, United States of America, Section of Infections of the Nervous System, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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