Deregulation of Type I IFN-Dependent Genes Correlates with Increased Susceptibility to Cytomegalovirus Acute Infection of Dicer Mutant Mice

Eleonore Ostermann; Lee Tuddenham; Cecile Macquin; Ghada Alsaleh; Julie Schreiber-Becker; Melanie Tanguy; Seiamak Bahram; Sebastien Pfeffer; Philippe Georgel

doi:10.1371/journal.pone.0043744

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Peer-reviewed

Research Article

Deregulation of Type I IFN-Dependent Genes Correlates with Increased Susceptibility to Cytomegalovirus Acute Infection of Dicer Mutant Mice

Eleonore Ostermann,

Affiliation Université de Strasbourg, EA 4438 Laboratoire d'Immunogénétique Moléculaire Humaine, Strasbourg, France
⨯
Lee Tuddenham,

Affiliation Université de Strasbourg, Architecture et Réactivité de l′ARN, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France
⨯
Cecile Macquin,

Affiliation Université de Strasbourg, EA 4438 Laboratoire d'Immunogénétique Moléculaire Humaine, Strasbourg, France
⨯
Ghada Alsaleh,

Affiliation Université de Strasbourg, EA 4438 Laboratoire de Physiopathologie des arthrites, Illkirch, France
⨯
Julie Schreiber-Becker,

Affiliation Université de Strasbourg, Architecture et Réactivité de l′ARN, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France
⨯
Melanie Tanguy,

Affiliation Université de Strasbourg, Architecture et Réactivité de l′ARN, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France
⨯
Seiamak Bahram,

Affiliation Université de Strasbourg, EA 4438 Laboratoire d'Immunogénétique Moléculaire Humaine, Strasbourg, France
⨯
Sebastien Pfeffer ,

* E-mail: s.pfeffer@ibmc-cnrs.unistra.fr (SP); pgeorgel@unistra.fr (PG)

Affiliation Université de Strasbourg, Architecture et Réactivité de l′ARN, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France
⨯
Philippe Georgel

* E-mail: s.pfeffer@ibmc-cnrs.unistra.fr (SP); pgeorgel@unistra.fr (PG)

Affiliation Université de Strasbourg, EA 4438 Laboratoire d'Immunogénétique Moléculaire Humaine, Strasbourg, France
⨯

Deregulation of Type I IFN-Dependent Genes Correlates with Increased Susceptibility to Cytomegalovirus Acute Infection of Dicer Mutant Mice

Eleonore Ostermann,
Lee Tuddenham,
Cecile Macquin,
Ghada Alsaleh,
Julie Schreiber-Becker,
Melanie Tanguy,
Seiamak Bahram,
Sebastien Pfeffer,
Philippe Georgel

Published: August 20, 2012
https://doi.org/10.1371/journal.pone.0043744

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