p53 Inactivation Upregulates p73 Expression through E2F-1 Mediated Transcription

Chaitali Tophkhane; Shi-He Yang; Yunbo Jiang; Zhikun Ma; Dharmalingam Subramaniam; Shrikant Anant; Shingo Yogosawa; Toshiyuki Sakai; Wan-Guo Liu; Susan Edgerton; Ann Thor; Xiaohe Yang

doi:10.1371/journal.pone.0043564

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Open Access

Peer-reviewed

Research Article

p53 Inactivation Upregulates p73 Expression through E2F-1 Mediated Transcription

Chaitali Tophkhane,

Affiliation Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯
Shi-He Yang,

Affiliation Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯
Yunbo Jiang,

Affiliation Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
⨯
Zhikun Ma,

Affiliation Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, United States of America
⨯
Dharmalingam Subramaniam,

Affiliation Department of Molecular & Integrative Physiology, KU Medical Center, The University of Kansas, Kansas City, Kansas, United States of America
⨯
Shrikant Anant,

Affiliation Department of Molecular & Integrative Physiology, KU Medical Center, The University of Kansas, Kansas City, Kansas, United States of America
⨯
Shingo Yogosawa,

Affiliation Department of Preventive Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
⨯
Toshiyuki Sakai,

Affiliation Department of Preventive Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
⨯
Wan-Guo Liu,

Affiliation Department of Genetics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Susan Edgerton,

Affiliation Department of Pathology, University of Colorado Denver School of Medicine, Aurora, Colorado, United States of America
⨯
Ann Thor,

Affiliation Department of Pathology, University of Colorado Denver School of Medicine, Aurora, Colorado, United States of America
⨯
Xiaohe Yang

* E-mail: xyang@nccu.edu

Affiliations Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, United States of America
⨯

p53 Inactivation Upregulates p73 Expression through E2F-1 Mediated Transcription

Chaitali Tophkhane,
Shi-He Yang,
Yunbo Jiang,
Zhikun Ma,
Dharmalingam Subramaniam,
Shrikant Anant,
Shingo Yogosawa,
Toshiyuki Sakai,
Wan-Guo Liu,
Susan Edgerton

Published: August 30, 2012
https://doi.org/10.1371/journal.pone.0043564

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Transfection
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Breast cancer
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