FcεR1-Mediated Mast Cell Reactivity Is Amplified through Prolonged Toll-Like Receptor-Ligand Treatment

Open Access

Peer-reviewed

Research Article

FcεR₁-Mediated Mast Cell Reactivity Is Amplified through Prolonged Toll-Like Receptor-Ligand Treatment

Rohit Saluja,

Affiliation Clinical Immunology and Allergy Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
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Ingrid Delin,

Affiliation Experimental Asthma and Allergy Research, The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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Gunnar P. Nilsson ,

Contributed equally to this work with: Gunnar P. Nilsson, Mikael Adner

* E-mail: Gunnar.P.Nilsson@ki.se

Affiliations Clinical Immunology and Allergy Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden
⨯
Mikael Adner

Contributed equally to this work with: Gunnar P. Nilsson, Mikael Adner

Affiliations Experimental Asthma and Allergy Research, The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden
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Mast cells
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Toll-like receptors
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Cross-linking
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Cell degranulation
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Cytokines
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Secretion
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Asthma
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MAPK signaling cascades
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