Breaking Tolerance in Transgenic Mice Expressing the Human TSH Receptor A-Subunit: Thyroiditis, Epitope Spreading and Adjuvant as a ‘Double Edged Sword’

Open Access

Peer-reviewed

Research Article

Sandra M. McLachlan ,

* E-mail: mclachlans@cshs.org

Affiliation Thyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute and UCLA School of Medicine, Los Angeles, California, United States of America
⨯
Holly A. Aliesky,

Affiliation Thyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute and UCLA School of Medicine, Los Angeles, California, United States of America
⨯
Chun-Rong Chen,

Affiliation Thyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute and UCLA School of Medicine, Los Angeles, California, United States of America
⨯
Gao Chong,

Affiliation Thyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute and UCLA School of Medicine, Los Angeles, California, United States of America
⨯
Basil Rapoport

Affiliation Thyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute and UCLA School of Medicine, Los Angeles, California, United States of America
⨯

Reader Comments (0)

Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Enzyme-linked immunoassays
Is the Subject Area "Enzyme-linked immunoassays" applicable to this article?

Thanks for your feedback.
Genetically modified animals
Is the Subject Area "Genetically modified animals" applicable to this article?

Thanks for your feedback.
Thyroid
Is the Subject Area "Thyroid" applicable to this article?

Thanks for your feedback.
Adenoviruses
Is the Subject Area "Adenoviruses" applicable to this article?

Thanks for your feedback.
Immunologic adjuvants
Is the Subject Area "Immunologic adjuvants" applicable to this article?

Thanks for your feedback.
Regulatory T cells
Is the Subject Area "Regulatory T cells" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.