FXR Controls the Tumor Suppressor NDRG2 and FXR Agonists Reduce Liver Tumor Growth and Metastasis in an Orthotopic Mouse Xenograft Model

Open Access

Peer-reviewed

Research Article

Ulrich Deuschle ,

* E-mail: ulrich.deuschle@phenex-pharma.com

Affiliation Department of Research, Phenex Pharmaceuticals AG, Heidelberg, Germany
⨯
Julia Schüler,

Affiliation Department of In Vivo Tumor Biology, Oncotest GmbH, Freiburg, Germany
⨯
Andreas Schulz,

Affiliation Department of Research, Phenex Pharmaceuticals AG, Heidelberg, Germany
⨯
Thomas Schlüter,

Affiliation Department of Research, Phenex Pharmaceuticals AG, Heidelberg, Germany
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Olaf Kinzel,

Affiliation Department of Research, Phenex Pharmaceuticals AG, Heidelberg, Germany
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Ulrich Abel,

Affiliation Department of Medicinal Chemistry, Merz Pharmaceuticals GmbH, Frankfurt, Germany
⨯
Claus Kremoser

Affiliation Department of Research, Phenex Pharmaceuticals AG, Heidelberg, Germany
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Hepatocellular carcinoma
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Mouse models
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Messenger RNA
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Lymph nodes
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