Systemic Preconditioning by a Prolyl Hydroxylase Inhibitor Promotes Prevention of Skin Flap Necrosis via HIF-1-Induced Bone Marrow-Derived Cells

• Mitsuru Takaku,

  Affiliation Department of Plastic and Reconstructive Surgery, The University of Tokushima Graduate School, Tokushima, Japan

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• Shuhei Tomita ,

  * E-mail: tomita@basic.med.tokushima-u.ac.jp

  Current address: Division of Molecular Pharmacology, Tottori University Faculty of Medicine, Yonago, Japan

  Affiliation Department of Pharmacology, The University of Tokushima Graduate School, Tokushima, Japan

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• Hirotsugu Kurobe,

  Affiliation Department of Cardiovascular Surgery, The University of Tokushima Graduate School, Tokushima, Japan

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• Yoshitaka Kihira,

  Affiliation Department of Pharmacology, The University of Tokushima Graduate School, Tokushima, Japan

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• Atsushi Morimoto,

  Affiliation Department of Plastic and Reconstructive Surgery, The University of Tokushima Graduate School, Tokushima, Japan

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• Mayuko Higashida,

  Affiliation Nutrition and Metabolism, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan

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• Yasumasa Ikeda,

  Affiliation Department of Pharmacology, The University of Tokushima Graduate School, Tokushima, Japan

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• Akira Ushiyama,

  Affiliation Department of Environmental Health, National Institute of Public Health, Saitama, Japan

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• Ichiro Hashimoto,

  Affiliation Department of Plastic and Reconstructive Surgery, The University of Tokushima Graduate School, Tokushima, Japan

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• Hideki Nakanishi,

  Affiliation Department of Plastic and Reconstructive Surgery, The University of Tokushima Graduate School, Tokushima, Japan

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• Toshiaki Tamaki

  Affiliation Department of Pharmacology, The University of Tokushima Graduate School, Tokushima, Japan

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