The Human EKC/KEOPS Complex Is Recruited to Cullin2 Ubiquitin Ligases by the Human Tumour Antigen PRAME

Adalberto Costessi; Nawel Mahrour; Vikram Sharma; Rieka Stunnenberg; Marieke A. Stoel; Esther Tijchon; Joan W. Conaway; Ronald C. Conaway; Hendrik G. Stunnenberg

doi:10.1371/journal.pone.0042822

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Peer-reviewed

Research Article

The Human EKC/KEOPS Complex Is Recruited to Cullin2 Ubiquitin Ligases by the Human Tumour Antigen PRAME

Adalberto Costessi,

Affiliation Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands
⨯
Nawel Mahrour,

Affiliation Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
⨯
Vikram Sharma,

Affiliation Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands
⨯
Rieka Stunnenberg,

Affiliation Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands
⨯
Marieke A. Stoel,

Affiliation Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands
⨯
Esther Tijchon,

Affiliation Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands
⨯
Joan W. Conaway,

Affiliations Stowers Institute for Medical Research, Kansas City, Missouri, United States of America, Department of Biochemistry and Molecular Biology, Kansas University Medical Center, Kansas City, Kansas, United States of America
⨯
Ronald C. Conaway,

Affiliations Stowers Institute for Medical Research, Kansas City, Missouri, United States of America, Department of Biochemistry and Molecular Biology, Kansas University Medical Center, Kansas City, Kansas, United States of America
⨯
Hendrik G. Stunnenberg

* E-mail: H.Stunnenberg@ncmls.ru.nl

Affiliation Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands
⨯

The Human EKC/KEOPS Complex Is Recruited to Cullin2 Ubiquitin Ligases by the Human Tumour Antigen PRAME

Adalberto Costessi,
Nawel Mahrour,
Vikram Sharma,
Rieka Stunnenberg,
Marieke A. Stoel,
Esther Tijchon,
Joan W. Conaway,
Ronald C. Conaway,
Hendrik G. Stunnenberg

Published: August 13, 2012
https://doi.org/10.1371/journal.pone.0042822

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Ligases
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Immunoprecipitation
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Testicular cancer
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Protein complexes
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Ubiquitin ligases
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