Role of Toll Like Receptors in Irritable Bowel Syndrome: Differential Mucosal Immune Activation According to the Disease Subtype

Liliana Belmonte; Stéphanie Beutheu Youmba; Nathalie Bertiaux-Vandaële; Michel Antonietti; Stéphane Lecleire; Alberto Zalar; Guillaume Gourcerol; Anne-Marie Leroi; Pierre Déchelotte; Moïse Coëffier; Philippe Ducrotté

doi:10.1371/journal.pone.0042777

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Open Access

Peer-reviewed

Research Article

Role of Toll Like Receptors in Irritable Bowel Syndrome: Differential Mucosal Immune Activation According to the Disease Subtype

Liliana Belmonte ,

* E-mail: liliana.belmonte-zalar@inv.univ-rouen.fr

Affiliations INSERM Unit U1073, Rouen University, Rouen, France, Institute for Research and Innovation in Biomedicine, Rouen University, Rouen, France, Laboratory of Immunology, IIHema, Consejo Nacional de Investigaciones Científicas y Técnicas, Academy National of Medicine, Buenos Aires, Argentine
⨯
Stéphanie Beutheu Youmba,

Affiliations INSERM Unit U1073, Rouen University, Rouen, France, Institute for Research and Innovation in Biomedicine, Rouen University, Rouen, France
⨯
Nathalie Bertiaux-Vandaële,

Affiliation Gastroenterology Department, Rouen University Hospital, Rouen, France
⨯
Michel Antonietti,

Affiliation Gastroenterology Department, Rouen University Hospital, Rouen, France
⨯
Stéphane Lecleire,

Affiliations INSERM Unit U1073, Rouen University, Rouen, France, Institute for Research and Innovation in Biomedicine, Rouen University, Rouen, France, Gastroenterology Department, Rouen University Hospital, Rouen, France
⨯
Alberto Zalar,

Affiliation Gastroenterology Department, Rouen University Hospital, Rouen, France
⨯
Guillaume Gourcerol,

Affiliations INSERM Unit U1073, Rouen University, Rouen, France, Institute for Research and Innovation in Biomedicine, Rouen University, Rouen, France, Physiology Department, Rouen University Hospital, Rouen, France
⨯
Anne-Marie Leroi,

Affiliations INSERM Unit U1073, Rouen University, Rouen, France, Institute for Research and Innovation in Biomedicine, Rouen University, Rouen, France, Physiology Department, Rouen University Hospital, Rouen, France
⨯
Pierre Déchelotte,

Affiliations INSERM Unit U1073, Rouen University, Rouen, France, Institute for Research and Innovation in Biomedicine, Rouen University, Rouen, France, Nutrition Unit, Rouen University Hospital, Rouen, France
⨯
Moïse Coëffier,

Affiliations INSERM Unit U1073, Rouen University, Rouen, France, Institute for Research and Innovation in Biomedicine, Rouen University, Rouen, France, Nutrition Unit, Rouen University Hospital, Rouen, France
⨯
Philippe Ducrotté

Affiliations INSERM Unit U1073, Rouen University, Rouen, France, Institute for Research and Innovation in Biomedicine, Rouen University, Rouen, France, Gastroenterology Department, Rouen University Hospital, Rouen, France
⨯

Role of Toll Like Receptors in Irritable Bowel Syndrome: Differential Mucosal Immune Activation According to the Disease Subtype

Liliana Belmonte,
Stéphanie Beutheu Youmba,
Nathalie Bertiaux-Vandaële,
Michel Antonietti,
Stéphane Lecleire,
Alberto Zalar,
Guillaume Gourcerol,
Anne-Marie Leroi,
Pierre Déchelotte,
Moïse Coëffier

Published: August 17, 2012
https://doi.org/10.1371/journal.pone.0042777

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Colon
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Toll-like receptors
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Irritable bowel syndrome
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Gastrointestinal tract
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Inflammatory bowel disease
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