Cell Surface Estrogen Receptor Alpha Is Upregulated during Subchronic Metabolic Stress and Inhibits Neuronal Cell Degeneration

• Cristiana Barbati,

  Affiliations San Raffaele Institute Sulmona, L'Aquila, Italy, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

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• Marina Pierdominici,

  Affiliation Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

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• Lucrezia Gambardella,

  Affiliation Department of Therapeutic Research and Medicine Evaluation, Istituto Superiore di Sanità, Rome, Italy

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• Fiorella Malchiodi Albedi,

  Affiliation Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

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• Richard H. Karas,

  Affiliation Molecular Cardiology Research Institute, Tufts Medical Center, Boston, Massachusetts, United States of America

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• Giuseppe Rosano,

  Affiliation Department of Medical Sciences, IRCCS San Raffaele Pisana, Rome, Italy

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• Walter Malorni ,

  ¶These authors are joint senior authors on this work.

  Affiliations San Raffaele Institute Sulmona, L'Aquila, Italy, Department of Therapeutic Research and Medicine Evaluation, Istituto Superiore di Sanità, Rome, Italy

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• Elena Ortona

  * E-mail: ortona@iss.it

  ¶These authors are joint senior authors on this work.

  Affiliations San Raffaele Institute Sulmona, L'Aquila, Italy, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

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