Mutation Patterns of 16 Genes in Primary and Secondary Acute Myeloid Leukemia (AML) with Normal Cytogenetics

Marta Fernandez-Mercado; Bon Ham Yip; Andrea Pellagatti; Carwyn Davies; María José Larrayoz; Toshinori Kondo; Cristina Pérez; Sally Killick; Emma-Jane McDonald; María Dolores Odero; Xabier Agirre; Felipe Prósper; María José Calasanz; James S. Wainscoat; Jacqueline Boultwood

doi:10.1371/journal.pone.0042334

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Open Access

Peer-reviewed

Research Article

Mutation Patterns of 16 Genes in Primary and Secondary Acute Myeloid Leukemia (AML) with Normal Cytogenetics

Marta Fernandez-Mercado,

Affiliation LLR Molecular Haematology Unit, NDCLS, John Radcliffe Hospital, Oxford, United Kingdom
⨯
Bon Ham Yip,

Affiliation LLR Molecular Haematology Unit, NDCLS, John Radcliffe Hospital, Oxford, United Kingdom
⨯
Andrea Pellagatti,

Affiliation LLR Molecular Haematology Unit, NDCLS, John Radcliffe Hospital, Oxford, United Kingdom
⨯
Carwyn Davies,

Affiliation LLR Molecular Haematology Unit, NDCLS, John Radcliffe Hospital, Oxford, United Kingdom
⨯
María José Larrayoz,

Affiliation Department of Genetics, University of Navarra, Pamplona, Spain
⨯
Toshinori Kondo,

Affiliation Division of Hematology, Kawasaki Medical School, Okayama, Japan
⨯
Cristina Pérez,

Affiliation Laboratory of Myeloproliferative Syndromes, Oncology Area, Foundation for Applied Medical Research, Clínica Universitaria, Universidad de Navarra, Pamplona, Spain
⨯
Sally Killick,

Affiliation Department of Haematology, Royal Bournemouth Hospital, Bournemouth, United Kingdom
⨯
Emma-Jane McDonald,

Affiliation Department of Haematology, Royal Bournemouth Hospital, Bournemouth, United Kingdom
⨯
María Dolores Odero,

Affiliations Department of Genetics, University of Navarra, Pamplona, Spain, Division of Oncology, Center for Applied Medical Research, Universidad de Navarra, Pamplona, Spain
⨯
Xabier Agirre,

Affiliation Division of Cancer and Area of Cell Therapy and Hematology Service, Foundation for Applied Medical Research, Clínica Universitaria, Universidad de Navarra, Pamplona, Spain
⨯
Felipe Prósper,

Affiliation Division of Cancer and Area of Cell Therapy and Hematology Service, Foundation for Applied Medical Research, Clínica Universitaria, Universidad de Navarra, Pamplona, Spain
⨯
María José Calasanz,

Affiliation Department of Genetics, University of Navarra, Pamplona, Spain
⨯
James S. Wainscoat,

Affiliation LLR Molecular Haematology Unit, NDCLS, John Radcliffe Hospital, Oxford, United Kingdom
⨯
Jacqueline Boultwood

* E-mail: jacqueline.boultwood@ndcls.ox.ac.uk

Affiliation LLR Molecular Haematology Unit, NDCLS, John Radcliffe Hospital, Oxford, United Kingdom
⨯

Mutation Patterns of 16 Genes in Primary and Secondary Acute Myeloid Leukemia (AML) with Normal Cytogenetics

Marta Fernandez-Mercado,
Bon Ham Yip,
Andrea Pellagatti,
Carwyn Davies,
María José Larrayoz,
Toshinori Kondo,
Cristina Pérez,
Sally Killick,
Emma-Jane McDonald,
María Dolores Odero

Published: August 9, 2012
https://doi.org/10.1371/journal.pone.0042334

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