Protection against High-Dose Highly Pathogenic Mucosal SIV Challenge at Very Low Serum Neutralizing Titers of the Antibody-Like Molecule CD4-IgG2

• Pascal Poignard ,

  * E-mail: poignard@scripps.edu (PP); burton@scripps.edu (DRB)

  Affiliations Department of Immunology and Microbial Science and IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, International AIDS Vaccine Initiative, New York, New York, United States of America, The Centre d'Immunologie de Marseille-Luminy, and Institut National de la Santé et de la Recherche Medicale, and Centre National de la Recherche Scientifique, Marseille, France

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• Brian Moldt,

  Affiliation Department of Immunology and Microbial Science and IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America

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• Karla Maloveste,

  Current address: Amplimmune, Inc, Gaithersburg, Maryland, United States of America

  Affiliation The Centre d'Immunologie de Marseille-Luminy, and Institut National de la Santé et de la Recherche Medicale, and Centre National de la Recherche Scientifique, Marseille, France

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• Noëlie Campos,

  Current address: Laboratoire coopératif SPLICOS SAS IGMM-CNRS-UMR5535, Montpellier, France

  Affiliation The Centre d'Immunologie de Marseille-Luminy, and Institut National de la Santé et de la Recherche Medicale, and Centre National de la Recherche Scientifique, Marseille, France

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• William C. Olson,

  Affiliation Progenics Pharmaceuticals, Inc. Tarrytown, New York, United States of America

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• Eva Rakasz,

  Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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• David I. Watkins,

  Affiliations Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Pathology, University of Miami, Miami, Florida, United States of America

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• Dennis R. Burton

  * E-mail: poignard@scripps.edu (PP); burton@scripps.edu (DRB)

  Affiliations Department of Immunology and Microbial Science and IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Boston, Massachusetts, United States of America

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