Overexpression of the DEC1 Protein Induces Senescence In Vitro and Is Related to Better Survival in Esophageal Squamous Cell Carcinoma

Qing Xu; Peiqing Ma; Chenfei Hu; Lechuang Chen; Liyan Xue; Zaozao Wang; Mei Liu; Hongxia Zhu; Ningzhi Xu; Ning Lu

doi:10.1371/journal.pone.0041862

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Open Access

Peer-reviewed

Research Article

Overexpression of the DEC1 Protein Induces Senescence In Vitro and Is Related to Better Survival in Esophageal Squamous Cell Carcinoma

Qing Xu ,

Contributed equally to this work with: Qing Xu, Peiqing Ma

Affiliation Laboratory of Cell and Molecular Biology and State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Peiqing Ma ,

Contributed equally to this work with: Qing Xu, Peiqing Ma

Affiliation Department of Pathology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Chenfei Hu,

Affiliation Laboratory of Cell and Molecular Biology and State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Lechuang Chen,

Affiliation Laboratory of Cell and Molecular Biology and State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Liyan Xue,

Affiliation Department of Pathology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Zaozao Wang,

Affiliation Laboratory of Cell and Molecular Biology and State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Mei Liu,

Affiliation Laboratory of Cell and Molecular Biology and State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Hongxia Zhu,

Affiliation Laboratory of Cell and Molecular Biology and State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Ningzhi Xu ,

* E-mail: ningzhi.xu@gmail.com (NX); nlu03@126.com (NL)

Affiliation Laboratory of Cell and Molecular Biology and State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Ning Lu

* E-mail: ningzhi.xu@gmail.com (NX); nlu03@126.com (NL)

Affiliation Department of Pathology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯

Overexpression of the DEC1 Protein Induces Senescence In Vitro and Is Related to Better Survival in Esophageal Squamous Cell Carcinoma

Qing Xu,
Peiqing Ma,
Chenfei Hu,
Lechuang Chen,
Liyan Xue,
Zaozao Wang,
Mei Liu,
Hongxia Zhu,
Ningzhi Xu,
Ning Lu

Published: July 23, 2012
https://doi.org/10.1371/journal.pone.0041862

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