Large-Scale Identification of MicroRNA Targets in Murine Dgcr8-Deficient Embryonic Stem Cell Lines

Matthew P. A. Davis; Cei Abreu-Goodger; Stijn van Dongen; Dong Lu; Peri H. Tate; Nenad Bartonicek; Claudia Kutter; Pentao Liu; William C. Skarnes; Anton J. Enright; Ian Dunham

doi:10.1371/journal.pone.0041762

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Open Access

Peer-reviewed

Research Article

Large-Scale Identification of MicroRNA Targets in Murine Dgcr8-Deficient Embryonic Stem Cell Lines

Matthew P. A. Davis,

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, European Bioinformatics Institute, European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom
⨯
Cei Abreu-Goodger,

Affiliations European Bioinformatics Institute, European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom, National Laboratory of Genomics for Biodiversity (Langebio), Cinvestav, Irapuato, Guanajuato, Mexico
⨯
Stijn van Dongen,

Affiliation European Bioinformatics Institute, European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom
⨯
Dong Lu,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
⨯
Peri H. Tate,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
⨯
Nenad Bartonicek,

Affiliation European Bioinformatics Institute, European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom
⨯
Claudia Kutter,

Affiliation Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom
⨯
Pentao Liu,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
⨯
William C. Skarnes,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
⨯
Anton J. Enright,

Affiliation European Bioinformatics Institute, European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom
⨯
Ian Dunham

* E-mail: dunham@ebi.ac.uk

Affiliation European Bioinformatics Institute, European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom
⨯

Large-Scale Identification of MicroRNA Targets in Murine Dgcr8-Deficient Embryonic Stem Cell Lines

Matthew P. A. Davis,
Cei Abreu-Goodger,
Stijn van Dongen,
Dong Lu,
Peri H. Tate,
Nenad Bartonicek,
Claudia Kutter,
Pentao Liu,
William C. Skarnes,
Anton J. Enright

Published: August 17, 2012
https://doi.org/10.1371/journal.pone.0041762

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MicroRNAs
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Transfection
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Heterozygosity
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RNA sequencing
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Homozygosity
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Messenger RNA
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Cell cycle and cell division
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Untranslated regions
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