Vitamin D Responsive Elements within the HLA-DRB1 Promoter Region in Sardinian Multiple Sclerosis Associated Alleles

Eleonora Cocco; Alessandra Meloni; Maria Rita Murru; Daniela Corongiu; Stefania Tranquilli; Elisabetta Fadda; Raffaele Murru; Lucia Schirru; Maria Antonietta Secci; Gianna Costa; Isadora Asunis; Stefania Cuccu; Giuseppe Fenu; Lorena Lorefice; Nicola Carboni; Gioia Mura; Maria Cristina Rosatelli; Maria Giovanna Marrosu

doi:10.1371/journal.pone.0041678

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Research Article

Vitamin D Responsive Elements within the HLA-DRB1 Promoter Region in Sardinian Multiple Sclerosis Associated Alleles

Eleonora Cocco ,

Contributed equally to this work with: Eleonora Cocco, Alessandra Meloni

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Alessandra Meloni ,

Contributed equally to this work with: Eleonora Cocco, Alessandra Meloni

Affiliation Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Cagliari, Italy
⨯
Maria Rita Murru,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Daniela Corongiu,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Stefania Tranquilli,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Elisabetta Fadda,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Raffaele Murru,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Lucia Schirru,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Maria Antonietta Secci,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Gianna Costa,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Isadora Asunis,

Affiliation Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Cagliari, Italy
⨯
Stefania Cuccu,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Giuseppe Fenu,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Lorena Lorefice,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Nicola Carboni,

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
Gioia Mura,

Affiliation Centro di Psichiatria e Psicosomatica Azienda Ospedaliera Universitaria, Cagliari, Italy
⨯
Maria Cristina Rosatelli,

Affiliation Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
[ ... ],
Maria Giovanna Marrosu

* E-mail: gmarrosu@unica.it

Affiliation Centro Sclerosi Multipla, Dipartimento di Sanità pubblica, Medicina clinica e molecolare, University of Cagliari, Cagliari, Italy
⨯
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Vitamin D Responsive Elements within the HLA-DRB1 Promoter Region in Sardinian Multiple Sclerosis Associated Alleles

Eleonora Cocco,
Alessandra Meloni,
Maria Rita Murru,
Daniela Corongiu,
Stefania Tranquilli,
Elisabetta Fadda,
Raffaele Murru,
Lucia Schirru,
Maria Antonietta Secci,
Gianna Costa

Published: July 25, 2012
https://doi.org/10.1371/journal.pone.0041678

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Multiple sclerosis
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Vitamin D
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Promoter regions
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Haplotypes
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Alleles
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