Natural Product Ginsenoside 25-OCH3-PPD Inhibits Breast Cancer Growth and Metastasis through Down-Regulating MDM2

Wei Wang; Xu Zhang; Jiang-Jiang Qin; Sukesh Voruganti; Subhasree Ashok Nag; Ming-Hai Wang; Hui Wang; Ruiwen Zhang

doi:10.1371/journal.pone.0041586

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Open Access

Peer-reviewed

Research Article

Natural Product Ginsenoside 25-OCH₃-PPD Inhibits Breast Cancer Growth and Metastasis through Down-Regulating MDM2

Wei Wang,

Affiliations Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas, United States of America, Cancer Biology Center, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas, United States of America
⨯
Xu Zhang,

Affiliation Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas, United States of America
⨯
Jiang-Jiang Qin,

Affiliation Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas, United States of America
⨯
Sukesh Voruganti,

Affiliation Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas, United States of America
⨯
Subhasree Ashok Nag,

Affiliation Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas, United States of America
⨯
Ming-Hai Wang,

Affiliations Cancer Biology Center, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas, United States of America, Department of Biomedical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas, United States of America
⨯
Hui Wang,

Affiliation Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
⨯
Ruiwen Zhang

* E-mail: ruiwen.zhang@ttuhsc.edu

Affiliations Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas, United States of America, Cancer Biology Center, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas, United States of America
⨯

Natural Product Ginsenoside 25-OCH₃-PPD Inhibits Breast Cancer Growth and Metastasis through Down-Regulating MDM2

Wei Wang,
Xu Zhang,
Jiang-Jiang Qin,
Sukesh Voruganti,
Subhasree Ashok Nag,
Ming-Hai Wang,
Hui Wang,
Ruiwen Zhang

Published: July 23, 2012
https://doi.org/10.1371/journal.pone.0041586

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