Aldolase B Knockdown Prevents High Glucose-Induced Methylglyoxal Overproduction and Cellular Dysfunction in Endothelial Cells

Open Access

Peer-reviewed

Research Article

Jianghai Liu,

Affiliation Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
⨯
Timothy Chun-Ping Mak,

Affiliation Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Ali Banigesh,

Affiliation Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Kaushik Desai,

Affiliation Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Rui Wang,

Affiliation Department of Biology, Lakehead University, Thunder Bay, Ontario, Canada
⨯
Lingyun Wu

* E-mail: lwu@lakeheadu.ca

Affiliations Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, Department of Health Sciences, Lakehead University and Thunder Bay Regional Research Institute, Thunder Bay, Ontario, Canada
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Glucose
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Small interfering RNA
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Endothelial cells
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Transfection
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Transcription factors
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Cell membranes
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Glucose metabolism
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Diabetes mellitus
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