The Acute Phase Reactant Orosomucoid-1 Is a Bimodal Regulator of Angiogenesis with Time- and Context-Dependent Inhibitory and Stimulatory Properties

Open Access

Peer-reviewed

Research Article

Giovanni Ligresti,

Affiliation Department of Pathology, University of Washington, Seattle, Washington, United States of America
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Alfred C. Aplin,

Affiliation Department of Pathology, University of Washington, Seattle, Washington, United States of America
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Bruce E. Dunn,

Affiliations Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Pathology and Laboratory Medicine Service, Department of Veteran Affairs Medical Center, Milwaukee, Wisconsin, United States of America
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Ann Morishita,

Affiliation Department of Pathology, University of Washington, Seattle, Washington, United States of America
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Roberto F. Nicosia

* E-mail: roberto.nicosia@va.gov

Affiliations Pathology and Laboratory Medicine Services, Veterans Administration Puget Sound Health Care System, Seattle, Washington, United States of America, Department of Pathology, University of Washington, Seattle, Washington, United States of America
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Angiogenesis
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Macrophages
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Endothelial cells
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Signal inhibition
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Collagens
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Inflammation
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VEGF signaling
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Phosphorylation
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