The Anti-Tumorigenic Mushroom Agaricus blazei Murill Enhances IL-1β Production and Activates the NLRP3 Inflammasome in Human Macrophages

• Tsung-Teng Huang,

  Affiliations Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan, Republic of China, Department of Medical Biotechnology and Laboratory Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan, Republic of China, Laboratory of Nanomaterials, Chang Gung University, Taoyuan, Taiwan, Republic of China, Research Center of Bacterial Pathogenesis, Chang Gung University, Taoyuan, Taiwan, Republic of China

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• David M. Ojcius,

  Affiliations Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan, Republic of China, Health Sciences Research Institute and School of Natural Sciences, University of California Merced, Merced, California, United States of America

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• John D. Young,

  Affiliations Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan, Republic of China, Laboratory of Nanomaterials, Chang Gung University, Taoyuan, Taiwan, Republic of China, Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, New York, United States of America, Biochemical Engineering Research Center, Mingchi University of Technology, Taipei, Taiwan, Republic of China

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• Yi-Hui Wu,

  Affiliation Cancer Research Center, National Cheng Kung University Hospital, Tainan, Taiwan, Republic of China

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• Yun-Fei Ko,

  Affiliation Biochemical Engineering Research Center, Mingchi University of Technology, Taipei, Taiwan, Republic of China

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• Tsui-Yin Wong,

  Affiliations Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan, Republic of China, Laboratory of Nanomaterials, Chang Gung University, Taoyuan, Taiwan, Republic of China, Research Center of Bacterial Pathogenesis, Chang Gung University, Taoyuan, Taiwan, Republic of China

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• Cheng-Yeu Wu,

  Affiliations Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan, Republic of China, Laboratory of Nanomaterials, Chang Gung University, Taoyuan, Taiwan, Republic of China, Research Center of Bacterial Pathogenesis, Chang Gung University, Taoyuan, Taiwan, Republic of China

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• Chia-Chen Lu,

  Affiliation Department of Respiratory Therapy, Fu Jen Catholic University, Taipei, Taiwan, Republic of China

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• Hsin-Chih Lai

  * E-mail: hclai@mail.cgu.edu.tw

  Affiliations Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan, Republic of China, Department of Medical Biotechnology and Laboratory Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan, Republic of China, Research Center of Bacterial Pathogenesis, Chang Gung University, Taoyuan, Taiwan, Republic of China

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