Differential Regulation of Transcription Factors by Location-Specific EGF Receptor Signaling via a Spatio-Temporal Interplay of ERK Activation

Open Access

Peer-reviewed

Research Article

Peng Wu,

Affiliation The Department of Medical Genetics and Signal Transduction Research Group, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
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Ping Wee,

Affiliation The Department of Medical Genetics and Signal Transduction Research Group, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
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Jennifer Jiang,

Affiliation The Department of Medical Genetics and Signal Transduction Research Group, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
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Xinmei Chen,

Affiliation The Department of Medical Genetics and Signal Transduction Research Group, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
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Zhixiang Wang

* E-mail: zhixiang.wang@ualberta.ca

Affiliation The Department of Medical Genetics and Signal Transduction Research Group, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
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EGFR signaling
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Phosphorylation
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ERK signaling cascade
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Cell proliferation
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Endosomes
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Immunoblotting
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Cell membranes
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CHO cells
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