Immunotherapeutic Targeting of Membrane Hsp70-Expressing Tumors Using Recombinant Human Granzyme B

Mathias Gehrmann; Stefan Stangl; Andreas Kirschner; Gemma A. Foulds; Wolfgang Sievert; Brigitte T. Doß; Axel Walch; Alan G. Pockley; Gabriele Multhoff

doi:10.1371/journal.pone.0041341

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Peer-reviewed

Research Article

Immunotherapeutic Targeting of Membrane Hsp70-Expressing Tumors Using Recombinant Human Granzyme B

Mathias Gehrmann ,

Contributed equally to this work with: Mathias Gehrmann, Stefan Stangl

Affiliation Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München, and Clinical Cooperation Group (CCG) “Innate Immunity in Tumor Biology”, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Munich, Germany
⨯
Stefan Stangl ,

Contributed equally to this work with: Mathias Gehrmann, Stefan Stangl

Affiliation Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München, and Clinical Cooperation Group (CCG) “Innate Immunity in Tumor Biology”, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Munich, Germany
⨯
Andreas Kirschner,

Affiliation Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München, and Clinical Cooperation Group (CCG) “Innate Immunity in Tumor Biology”, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Munich, Germany
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Gemma A. Foulds,

Affiliations Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München, and Clinical Cooperation Group (CCG) “Innate Immunity in Tumor Biology”, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Munich, Germany, Department of Oncology, The Medical School, University of Sheffield, Sheffield, United Kingdom
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Wolfgang Sievert,

Affiliation Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München, and Clinical Cooperation Group (CCG) “Innate Immunity in Tumor Biology”, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Munich, Germany
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Brigitte T. Doß,

Affiliation Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München, and Clinical Cooperation Group (CCG) “Innate Immunity in Tumor Biology”, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Munich, Germany
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Axel Walch,

Affiliation Institute of Pathology, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Munich, Germany
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Alan G. Pockley,

Affiliation Department of Oncology, The Medical School, University of Sheffield, Sheffield, United Kingdom
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Gabriele Multhoff

* E-mail: gabriele.multhoff@lrz.tu-muenchen.de

Affiliation Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München, and Clinical Cooperation Group (CCG) “Innate Immunity in Tumor Biology”, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Munich, Germany
⨯

Immunotherapeutic Targeting of Membrane Hsp70-Expressing Tumors Using Recombinant Human Granzyme B

Mathias Gehrmann,
Stefan Stangl,
Andreas Kirschner,
Gemma A. Foulds,
Wolfgang Sievert,
Brigitte T. Doß,
Axel Walch,
Alan G. Pockley,
Gabriele Multhoff

Published: July 19, 2012
https://doi.org/10.1371/journal.pone.0041341

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