Assessment of Strain-Specific PrPSc Elongation Rates Revealed a Transformation of PrPSc Properties during Protein Misfolding Cyclic Amplification

Open Access

Peer-reviewed

Research Article

Assessment of Strain-Specific PrP^Sc Elongation Rates Revealed a Transformation of PrP^Sc Properties during Protein Misfolding Cyclic Amplification

Nuria Gonzalez-Montalban,

Affiliation Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Ilia V. Baskakov

* E-mail: Baskakov@umaryland.edu

Affiliations Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Sonication
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Prion diseases
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Hamsters
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Physical properties
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Signal amplification
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Convergent evolution
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Protein misfolding
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Scrapie
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