High Avidity Cytotoxic T Lymphocytes Can Be Selected into the Memory Pool but They Are Exquisitely Sensitive to Functional Impairment

Open Access

Peer-reviewed

Research Article

Victoria A. Brentville,

Affiliation Scancell Holdings plc, Academic Department of Clinical Oncology, City Hospital Campus, University of Nottingham, Nottingham, United Kingdom
⨯
Rachael L. Metheringham,

Affiliation Scancell Holdings plc, Academic Department of Clinical Oncology, City Hospital Campus, University of Nottingham, Nottingham, United Kingdom
⨯
Barbara Gunn,

Affiliation Scancell Holdings plc, Academic Department of Clinical Oncology, City Hospital Campus, University of Nottingham, Nottingham, United Kingdom
⨯
Lindy G. Durrant

* E-mail: lindy.durrant@nottingham.ac.uk

Affiliations Scancell Holdings plc, Academic Department of Clinical Oncology, City Hospital Campus, University of Nottingham, Nottingham, United Kingdom, Academic Department of Clinical Oncology, City Hospital Campus, University of Nottingham, Nottingham, United Kingdom
⨯

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T cells
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Immune response
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Cytotoxic T cells
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Enzyme-linked immunoassays
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Cancers and neoplasms
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Antibody response
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T cell receptors
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TCR signaling cascade
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