Ovarian Cancer Gene Therapy Using HPV-16 Pseudovirion Carrying the HSV-tk Gene

Chien-Fu Hung; An Jen Chiang; Hsiao-Hsuan Tsai; Martin G. Pomper; Tae Heung Kang; Richard R. Roden; T.-C. Wu

doi:10.1371/journal.pone.0040983

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Open Access

Peer-reviewed

Research Article

Ovarian Cancer Gene Therapy Using HPV-16 Pseudovirion Carrying the HSV-tk Gene

Chien-Fu Hung ,

* E-mail: chung2@jhmi.edu

Affiliations Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
An Jen Chiang,

Affiliations Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Department of Obstetrics and Gynecology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, Division of Obstetrics and Gynecology, National Yang-Ming University School of Medicine, Taipei, Taiwan, Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan
⨯
Hsiao-Hsuan Tsai,

Affiliation Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Martin G. Pomper,

Affiliation Department of Radiology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
⨯
Tae Heung Kang,

Affiliation Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Richard R. Roden,

Affiliations Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Department of Obstetrics and Gynecology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
T.-C. Wu

Affiliations Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Department of Obstetrics and Gynecology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Department of Molecular Microbiology and Immunology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯

Ovarian Cancer Gene Therapy Using HPV-16 Pseudovirion Carrying the HSV-tk Gene

Chien-Fu Hung,
An Jen Chiang,
Hsiao-Hsuan Tsai,
Martin G. Pomper,
Tae Heung Kang,
Richard R. Roden,
T.-C. Wu

Published: July 17, 2012
https://doi.org/10.1371/journal.pone.0040983

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Ovarian cancer
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HPV-16
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Cancer treatment
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Intraperitoneal injections
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Luminescence
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Gene therapy
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Genetically modified animals
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