Contribution of Hypothermia and CB1 Receptor Activation to Protective Effects of TAK-937, a Cannabinoid Receptor Agonist, in Rat Transient MCAO Model

Open Access

Peer-reviewed

Research Article

Contribution of Hypothermia and CB₁ Receptor Activation to Protective Effects of TAK-937, a Cannabinoid Receptor Agonist, in Rat Transient MCAO Model

Noriko Suzuki,

Affiliation Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Motohisa Suzuki,

Affiliation Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
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Kazuhiro Hamajo,

Affiliation Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Koji Murakami,

Affiliations Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan, Division of Pharmaceutical Sciences, Kanazawa University Graduate School of Natural Science and Technology, Kanazawa, Japan
⨯
Tetsuya Tsukamoto,

Affiliation Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Masato Shimojo

* E-mail: Shimojo_Masato@takeda.co.jp

Affiliation Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯

Hypothermia
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Body temperature
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Rectum
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Receptor antagonist therapy
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Reperfusion
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Drug administration
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Ischemic stroke
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Cannabinoids
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