Intracellular Retention of ABL Kinase Inhibitors Determines Commitment to Apoptosis in CML Cells

• Daniel B. Lipka ,

  Contributed equally to this work with: Daniel B. Lipka, Marie-Christine Wagner

  Affiliations Department of Hematology and Oncology, University Medical Center, Otto-von-Guericke-University, Magdeburg, Germany, Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany

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• Marie-Christine Wagner ,

  Contributed equally to this work with: Daniel B. Lipka, Marie-Christine Wagner

  Affiliation Department of Hematology and Oncology, University Medical Center, Otto-von-Guericke-University, Magdeburg, Germany

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• Marek Dziadosz,

  Affiliation Institute of Forensic Medicine, University Medical Center, Otto-von-Guericke-University, Magdeburg, Germany

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• Tina Schnöder,

  Affiliation Department of Hematology and Oncology, University Medical Center, Otto-von-Guericke-University, Magdeburg, Germany

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• Florian Heidel,

  Affiliation Department of Hematology and Oncology, University Medical Center, Otto-von-Guericke-University, Magdeburg, Germany

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• Mirle Schemionek,

  Affiliations Department of Medicine A (Hematology, Oncology and Pneumology), University of Münster, Münster, Germany, Department of Oncology, Hematology and Stem Cell Transplantation, University Medical Center, Rheinisch-Westfaelische Technische Hochschule, Aachen, Germany

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• Junia V. Melo,

  Affiliations Department of Haematology, Centre for Cancer Biology, University of Adelaide, Adelaide, Australia, Department of Haematology, Imperial College London, London, United Kingdom

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• Thomas Kindler,

  Affiliation Third Department of Medicine, University Medical Center, Johannes Gutenberg-University, Mainz, Germany

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• Carsten Müller-Tidow,

  Affiliation Department of Medicine A (Hematology, Oncology and Pneumology), University of Münster, Münster, Germany

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• Steffen Koschmieder,

  Affiliations Department of Medicine A (Hematology, Oncology and Pneumology), University of Münster, Münster, Germany, Department of Oncology, Hematology and Stem Cell Transplantation, University Medical Center, Rheinisch-Westfaelische Technische Hochschule, Aachen, Germany

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• Thomas Fischer

  * E-mail: thomas.fischer@med.ovgu.de

  Affiliation Department of Hematology and Oncology, University Medical Center, Otto-von-Guericke-University, Magdeburg, Germany

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