IL-17A Facilitates Platelet Function through the ERK2 Signaling Pathway in Patients with Acute Coronary Syndrome

Shuang Zhang; Jing Yuan; Miao Yu; Hong Fan; Zhang-Qiang Guo; Rui Yang; He-Ping Guo; Yu-Hua Liao; Min Wang

doi:10.1371/journal.pone.0040641

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Open Access

Peer-reviewed

Research Article

IL-17A Facilitates Platelet Function through the ERK2 Signaling Pathway in Patients with Acute Coronary Syndrome

Shuang Zhang ,

Contributed equally to this work with: Shuang Zhang, Jing Yuan, Miao Yu

Affiliation Laboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Huazhong University of Science and Technology, Wuhan, China
⨯
Jing Yuan ,

Contributed equally to this work with: Shuang Zhang, Jing Yuan, Miao Yu

Affiliation Laboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Huazhong University of Science and Technology, Wuhan, China
⨯
Miao Yu ,

Contributed equally to this work with: Shuang Zhang, Jing Yuan, Miao Yu

Affiliation Laboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Huazhong University of Science and Technology, Wuhan, China
⨯
Hong Fan,

Affiliation Department of Emergency Medicine, Union Hospital, Huazhong University of Science and Technology, Wuhan, China
⨯
Zhang-Qiang Guo,

Affiliation Department of Cardiology, Pu Ai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Rui Yang,

Affiliation Department of Hematology, Union Hospital, Huazhong University of Science and Technology, Wuhan, China
⨯
He-Ping Guo,

Affiliation Laboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Huazhong University of Science and Technology, Wuhan, China
⨯
Yu-Hua Liao ,

* E-mail: wm_xmy@whuh.com (MW); liaoyh27@163.com (YHL)

Affiliation Laboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Huazhong University of Science and Technology, Wuhan, China
⨯
Min Wang

* E-mail: wm_xmy@whuh.com (MW); liaoyh27@163.com (YHL)

Affiliation Laboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Huazhong University of Science and Technology, Wuhan, China
⨯

IL-17A Facilitates Platelet Function through the ERK2 Signaling Pathway in Patients with Acute Coronary Syndrome

Shuang Zhang,
Jing Yuan,
Miao Yu,
Hong Fan,
Zhang-Qiang Guo,
Rui Yang,
He-Ping Guo,
Yu-Hua Liao,
Min Wang

Published: July 11, 2012
https://doi.org/10.1371/journal.pone.0040641

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Platelet aggregation
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Platelets
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Platelet activation
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Blood plasma
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Cell signaling
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