Rac1 Activation Driven by 14-3-3ζ Dimerization Promotes Prostate Cancer Cell-Matrix Interactions, Motility and Transendothelial Migration

Open Access

Peer-reviewed

Research Article

Anna Goc,

Affiliations Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, Augusta, Georgia, United States of America, Charlie Norwood VA Medical Center, Augusta, Georgia, United States of America
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Maha Abdalla,

Affiliations Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, Augusta, Georgia, United States of America, Charlie Norwood VA Medical Center, Augusta, Georgia, United States of America
⨯
Ahmad Al-Azayzih,

Affiliations Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, Augusta, Georgia, United States of America, Charlie Norwood VA Medical Center, Augusta, Georgia, United States of America
⨯
Payaningal R. Somanath

* E-mail: sshenoy@georgiahealth.edu

Affiliations Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, Augusta, Georgia, United States of America, Charlie Norwood VA Medical Center, Augusta, Georgia, United States of America, Department of Medicine, Georgia Health Sciences University, Augusta, Georgia, United States of America
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Prostate cancer
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Cancer cell migration
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Extracellular matrix proteins
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Cell migration
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Transfection
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Dimerization
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Phosphorylation
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Protein interactions
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