High-Affinity Target Binding Engineered via Fusion of a Single-Domain Antibody Fragment with a Ligand-Tailored SH3 Domain

• Annika Järviluoma,

  Affiliation Department of Virology, Haartman Institute, University of Helsinki, Helsinki, Finland

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• Tomas Strandin,

  Affiliation Department of Virology, Haartman Institute, University of Helsinki, Helsinki, Finland

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• Sebastian Lülf,

  Affiliation Department of Physical Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany

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• Jérôme Bouchet,

  Affiliations Institut Cochin, CNRS (UMR8104), Université Paris Descartes, Paris, France, Inserm U1016, Paris, France

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• Anna R. Mäkelä,

  Affiliation NEXT Biomed Technologies NBT Oy, Helsinki, Finland

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• Matthias Geyer,

  Affiliation Department of Physical Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany

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• Serge Benichou,

  Affiliations Institut Cochin, CNRS (UMR8104), Université Paris Descartes, Paris, France, Inserm U1016, Paris, France

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• Kalle Saksela

  * E-mail: kalle.saksela@helsinki.fi

  Affiliations Department of Virology, Haartman Institute, University of Helsinki, Helsinki, Finland, HUSLAB, Helsinki University Central Hospital, Helsinki, Finland

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