Antibody-Antigen-Adjuvant Conjugates Enable Co-Delivery of Antigen and Adjuvant to Dendritic Cells in Cis but Only Have Partial Targeting Specificity

• Martin Kreutz ,

  Contributed equally to this work with: Martin Kreutz, Benoit Giquel, Qin Hu

  Affiliations Peter Gorer Department of Immunobiology, King’s College London, Guy’s Hospital, London, United Kingdom, Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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• Benoit Giquel ,

  Contributed equally to this work with: Martin Kreutz, Benoit Giquel, Qin Hu

  Affiliation Peter Gorer Department of Immunobiology, King’s College London, Guy’s Hospital, London, United Kingdom

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• Qin Hu ,

  Contributed equally to this work with: Martin Kreutz, Benoit Giquel, Qin Hu

  Affiliation Peter Gorer Department of Immunobiology, King’s College London, Guy’s Hospital, London, United Kingdom

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• Ram Abuknesha,

  Affiliation Pharmaceutical Science Division, King’s College London, London, United Kingdom

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• Satoshi Uematsu,

  Affiliation Laboratory of Host Defense, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan

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• Shizuo Akira,

  Affiliation Laboratory of Host Defense, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan

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• Frank O. Nestle,

  Affiliation Cutaneous Medicine and Immunotherapy Unit, King’s College London, Guy’s Hospital, London, United Kingdom

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• Sandra S. Diebold

  * E-mail: sandra.diebold@kcl.ac.uk

  Affiliation Peter Gorer Department of Immunobiology, King’s College London, Guy’s Hospital, London, United Kingdom

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