Mutagenesis-Mediated Decrease of Pathogenicity as a Feature of the Mutant Spectrum of a Viral Population

Open Access

Peer-reviewed

Research Article

Marta Sanz-Ramos,

Current address: Division of Virology, National Institute for Medical Research, Mill Hill, London, United Kingdom

Affiliations Centro de Investigación en Sanidad Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (CISA-INIA), Valdeolmos, Madrid, Spain, Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Campus de Cantoblanco, Madrid, Spain
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Teresa Rodríguez-Calvo,

Affiliation Centro de Investigación en Sanidad Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (CISA-INIA), Valdeolmos, Madrid, Spain
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Noemí Sevilla

* E-mail: sevilla@inia.es

Affiliation Centro de Investigación en Sanidad Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (CISA-INIA), Valdeolmos, Madrid, Spain
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Cloning
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Mammalian genomics
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Mutagenesis
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Viral genomics
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Substitution mutation
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Nucleotide sequencing
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Microbial mutation
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Viral replication
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