Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses

Rachel Grimley; Oxana Polyakova; Jessica Vamathevan; Joanne McKenary; Brian Hayes; Champa Patel; Janet Smith; Angela Bridges; Andrew Fosberry; Anshu Bhardwaja; Bernadette Mouzon; Chun-Wa Chung; Nathalie Barrett; Nicola Richmond; Sundip Modha; Roberto Solari

doi:10.1371/journal.pone.0039847

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Peer-reviewed

Research Article

Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses

Rachel Grimley ,

Contributed equally to this work with: Rachel Grimley, Oxana Polyakova, Jessica Vamathevan

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Oxana Polyakova ,

Contributed equally to this work with: Rachel Grimley, Oxana Polyakova, Jessica Vamathevan

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Jessica Vamathevan ,

Contributed equally to this work with: Rachel Grimley, Oxana Polyakova, Jessica Vamathevan

Affiliations Computational Biology, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom, Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Joanne McKenary,

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Brian Hayes,

Affiliation Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Champa Patel,

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Janet Smith,

Affiliation Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Angela Bridges,

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Andrew Fosberry,

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Anshu Bhardwaja,

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Bernadette Mouzon,

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Chun-Wa Chung,

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Nathalie Barrett,

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Nicola Richmond,

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
Sundip Modha,

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
[ ... ],
Roberto Solari

* E-mail: roberto.2.solari@gsk.com

Affiliation Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom
⨯
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Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses

Rachel Grimley,
Oxana Polyakova,
Jessica Vamathevan,
Joanne McKenary,
Brian Hayes,
Champa Patel,
Janet Smith,
Angela Bridges,
Andrew Fosberry,
Anshu Bhardwaja

Published: July 6, 2012
https://doi.org/10.1371/journal.pone.0039847

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