Impact of Large Aggregated Uricases and PEG Diol on Accelerated Blood Clearance of PEGylated Canine Uricase

• Chun Zhang,

  Affiliations State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology, Shanghai, People’s Republic of China, Modern TCM Institute, Linyi University, Linyi, Shandong, People’s Republic of China

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• Kai Fan,

  Affiliation Fagen Biomedical Inc., Chongqing, People’s Republic of China

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• Xuefeng Ma,

  Affiliation Fagen Biomedical Inc., Chongqing, People’s Republic of China

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• Dongzhi Wei

  * E-mail: dzhwei@ecust.edu.cn

  Affiliation State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology, Shanghai, People’s Republic of China

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