Enzymatic Degradation of PrPSc by a Protease Secreted from Aeropyrum pernix K1

Open Access

Peer-reviewed

Research Article

Enzymatic Degradation of PrP^Sc by a Protease Secreted from Aeropyrum pernix K1

Marko Šnajder,

Affiliation Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia
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Tanja Vilfan,

Affiliation Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia
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Maja Černilec,

Affiliation Blood Transfusion Center of Slovenia, Ljubljana, Slovenia
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Ruth Rupreht,

Affiliation Blood Transfusion Center of Slovenia, Ljubljana, Slovenia
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Mara Popović,

Affiliation Medical Faculty, University of Ljubljana, Ljubljana, Slovenia
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Polona Juntes,

Affiliation Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia
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Vladka Čurin Šerbec,

Affiliation Blood Transfusion Center of Slovenia, Ljubljana, Slovenia
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Nataša Poklar Ulrih

* E-mail: natasa.poklar@bf.uni-lj.si

Affiliations Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia, Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins (CipKeBiP), Ljubljana, Slovenia
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Proteases
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Monoclonal antibodies
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Enzyme purification
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Gel filtration
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Nitrocellulose
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Metalloproteases
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SDS denaturation techniques
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Animal prion diseases
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