Temporal Network Based Analysis of Cell Specific Vein Graft Transcriptome Defines Key Pathways and Hub Genes in Implantation Injury

Manoj Bhasin; Zhen Huang; Leena Pradhan-Nabzdyk; Junaid Y. Malek; Philip J. LoGerfo; Mauricio Contreras; Patrick Guthrie; Eva Csizmadia; Nicholas Andersen; Olivier Kocher; Christiane Ferran; Frank W. LoGerfo

doi:10.1371/journal.pone.0039123

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Peer-reviewed

Research Article

Temporal Network Based Analysis of Cell Specific Vein Graft Transcriptome Defines Key Pathways and Hub Genes in Implantation Injury

Manoj Bhasin,

Affiliation Genomics and Proteomics Center, Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Zhen Huang,

Affiliation Division of Vascular and Endovascular Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Leena Pradhan-Nabzdyk,

Affiliation Division of Vascular and Endovascular Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Junaid Y. Malek,

Affiliation Division of Vascular and Endovascular Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Philip J. LoGerfo,

Affiliation Genomics and Proteomics Center, Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Mauricio Contreras,

Affiliation Division of Vascular and Endovascular Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Patrick Guthrie,

Affiliation Division of Vascular and Endovascular Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Eva Csizmadia,

Affiliation Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Nicholas Andersen,

Affiliation Division of Vascular and Endovascular Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Olivier Kocher,

Affiliation Deptartment of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Christiane Ferran ,

* E-mail: flogerfo@bidmc.harvard.edu (FWL); cferran@bidmc.harvard.edu (CF)

Affiliations Division of Vascular and Endovascular Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Vascular Biology Research and Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Frank W. LoGerfo

* E-mail: flogerfo@bidmc.harvard.edu (FWL); cferran@bidmc.harvard.edu (CF)

Affiliation Division of Vascular and Endovascular Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Temporal Network Based Analysis of Cell Specific Vein Graft Transcriptome Defines Key Pathways and Hub Genes in Implantation Injury

Manoj Bhasin,
Zhen Huang,
Leena Pradhan-Nabzdyk,
Junaid Y. Malek,
Philip J. LoGerfo,
Mauricio Contreras,
Patrick Guthrie,
Eva Csizmadia,
Nicholas Andersen,
Olivier Kocher

Published: June 15, 2012
https://doi.org/10.1371/journal.pone.0039123

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