A Monoclonal Antibody-GDNF Fusion Protein Is Not Neuroprotective and Is Associated with Proliferative Pancreatic Lesions in Parkinsonian Monkeys

• Sachiko Ohshima-Hosoyama ,

  Contributed equally to this work with: Sachiko Ohshima-Hosoyama, Heather A. Simmons

  Affiliation Preclinical Parkinson’s Research Program, Wisconsin National Primate Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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• Heather A. Simmons ,

  Contributed equally to this work with: Sachiko Ohshima-Hosoyama, Heather A. Simmons

  Affiliation Wisconsin National Primate Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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• Nichole Goecks,

  Affiliation Wisconsin National Primate Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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• Valerie Joers,

  Affiliations Preclinical Parkinson’s Research Program, Wisconsin National Primate Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Neuroscience Training Program, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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• Christine R. Swanson,

  Affiliations Preclinical Parkinson’s Research Program, Wisconsin National Primate Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Neuroscience Training Program, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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• Viktoriya Bondarenko,

  Affiliation Preclinical Parkinson’s Research Program, Wisconsin National Primate Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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• Rebecca Velotta,

  Affiliation Preclinical Parkinson’s Research Program, Wisconsin National Primate Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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• Kevin Brunner,

  Affiliation Wisconsin National Primate Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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• Laura D. Wood,

  Affiliation Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Ralph H. Hruban,

  Affiliation Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Marina E. Emborg

  * E-mail: emborg@primate.wisc.edu

  Affiliations Preclinical Parkinson’s Research Program, Wisconsin National Primate Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Wisconsin National Primate Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Neuroscience Training Program, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Department of Medical Physics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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