Gene Silencing of Toll-Like Receptor 2 Inhibits Proliferation of Human Liver Cancer Cells and Secretion of Inflammatory Cytokines

Yuzheng Huang; Bing Cai; Ming Xu; Zhiqin Qiu; Yonghui Tao; Ying Zhang; Jie Wang; Yongliang Xu; Yonghua Zhou; Jing Yang; Xiaofeng Han; Qi Gao

doi:10.1371/journal.pone.0038890

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Open Access

Peer-reviewed

Research Article

Gene Silencing of Toll-Like Receptor 2 Inhibits Proliferation of Human Liver Cancer Cells and Secretion of Inflammatory Cytokines

Yuzheng Huang ,

Contributed equally to this work with: Yuzheng Huang, Bing Cai

Affiliation Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China
⨯
Bing Cai ,

Contributed equally to this work with: Yuzheng Huang, Bing Cai

Affiliation Wuxi People’s Hospital of Nanjing Medical University, Wuxi, Jiangsu, China
⨯
Ming Xu,

Affiliation Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China
⨯
Zhiqin Qiu,

Affiliation Wuxi Secondly People’s Hospital of Nanjing Medical University, Wuxi, Jiangsu, China
⨯
Yonghui Tao,

Affiliation Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China
⨯
Ying Zhang,

Affiliation Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China
⨯
Jie Wang,

Affiliation Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China
⨯
Yongliang Xu,

Affiliation Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China
⨯
Yonghua Zhou,

Affiliation Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China
⨯
Jing Yang,

Affiliation Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China
⨯
Xiaofeng Han ,

* E-mail: xfenghan@hotmail.com (XH); gaoqi54@hotmail.com (QG)

Affiliation Wuxi Secondly People’s Hospital of Nanjing Medical University, Wuxi, Jiangsu, China
⨯
Qi Gao

* E-mail: xfenghan@hotmail.com (XH); gaoqi54@hotmail.com (QG)

Affiliation Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China
⨯

Gene Silencing of Toll-Like Receptor 2 Inhibits Proliferation of Human Liver Cancer Cells and Secretion of Inflammatory Cytokines

Yuzheng Huang,
Bing Cai,
Ming Xu,
Zhiqin Qiu,
Yonghui Tao,
Ying Zhang,
Jie Wang,
Yongliang Xu,
Yonghua Zhou,
Jing Yang

Published: July 16, 2012
https://doi.org/10.1371/journal.pone.0038890

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Toll-like receptors
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Small interfering RNA
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Hepatocellular carcinoma
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Transfection
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Cancer treatment
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Lung and intrathoracic tumors
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Breast cancer
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