Downregulated miR-195 Detected in Preeclamptic Placenta Affects Trophoblast Cell Invasion via Modulating ActRIIA Expression

Yang Bai; Weiwei Yang; Hui-xia Yang; Qinping Liao; Gang Ye; Guodong Fu; Lei Ji; Peng Xu; Hao Wang; Yu-xia Li; Chun Peng; Yan-ling Wang

doi:10.1371/journal.pone.0038875

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Open Access

Peer-reviewed

Research Article

Downregulated miR-195 Detected in Preeclamptic Placenta Affects Trophoblast Cell Invasion via Modulating ActRIIA Expression

Yang Bai,

Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, Graduate School of Chinese Academy of Sciences, Beijing, China
⨯
Weiwei Yang,

Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, Graduate School of Chinese Academy of Sciences, Beijing, China
⨯
Hui-xia Yang,

Affiliation Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China
⨯
Qinping Liao,

Affiliation Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China
⨯
Gang Ye,

Affiliation Department of Biology, York University, Toronto, Ontario, Canada
⨯
Guodong Fu,

Affiliation Department of Biology, York University, Toronto, Ontario, Canada
⨯
Lei Ji,

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
⨯
Peng Xu,

Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, Graduate School of Chinese Academy of Sciences, Beijing, China
⨯
Hao Wang,

Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, Graduate School of Chinese Academy of Sciences, Beijing, China
⨯
Yu-xia Li,

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
⨯
Chun Peng ,

* E-mail: wangyl@ioz.ac.cn (YLW); cpeng@yorku.ca (CP)

Affiliation Department of Biology, York University, Toronto, Ontario, Canada
⨯
Yan-ling Wang

* E-mail: wangyl@ioz.ac.cn (YLW); cpeng@yorku.ca (CP)

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
⨯

Downregulated miR-195 Detected in Preeclamptic Placenta Affects Trophoblast Cell Invasion via Modulating ActRIIA Expression

Yang Bai,
Weiwei Yang,
Hui-xia Yang,
Qinping Liao,
Gang Ye,
Guodong Fu,
Lei Ji,
Peng Xu,
Hao Wang,
Yu-xia Li

Published: June 19, 2012
https://doi.org/10.1371/journal.pone.0038875

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MicroRNAs
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Transfection
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Placenta
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Hypertensive disorders in pregnancy
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