Humanized Mice Recapitulate Key Features of HIV-1 Infection: A Novel Concept Using Long-Acting Anti-Retroviral Drugs for Treating HIV-1

Marc Nischang; Roger Sutmuller; Gustavo Gers-Huber; Annette Audigé; Duo Li; Mary-Aude Rochat; Stefan Baenziger; Ursula Hofer; Erika Schlaepfer; Stephan Regenass; Katie Amssoms; Bart Stoops; Anja Van Cauwenberge; Daniel Boden; Guenter Kraus; Roberto F. Speck

doi:10.1371/journal.pone.0038853

Loading metrics

Open Access

Peer-reviewed

Research Article

Humanized Mice Recapitulate Key Features of HIV-1 Infection: A Novel Concept Using Long-Acting Anti-Retroviral Drugs for Treating HIV-1

Marc Nischang,

Affiliation Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland
⨯
Roger Sutmuller,

Affiliation Tibotec BVBA, Beerse, Belgium
⨯
Gustavo Gers-Huber,

Affiliation Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland
⨯
Annette Audigé,

Affiliation Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland
⨯
Duo Li,

Affiliation Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland
⨯
Mary-Aude Rochat,

Affiliation Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland
⨯
Stefan Baenziger,

Affiliation Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland
⨯
Ursula Hofer,

Affiliation Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland
⨯
Erika Schlaepfer,

Affiliation Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland
⨯
Stephan Regenass,

Affiliation Clinical Immunology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland
⨯
Katie Amssoms,

Affiliation Tibotec BVBA, Beerse, Belgium
⨯
Bart Stoops,

Affiliation Tibotec BVBA, Beerse, Belgium
⨯
Anja Van Cauwenberge,

Affiliation Tibotec BVBA, Beerse, Belgium
⨯
Daniel Boden,

Affiliation Tibotec BVBA, Beerse, Belgium
⨯
Guenter Kraus,

Affiliation Tibotec BVBA, Beerse, Belgium
⨯
[ ... ],
Roberto F. Speck

* E-mail: roberto.speck@usz.ch

Affiliation Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland
⨯
[ view all ]
[ view less ]

Humanized Mice Recapitulate Key Features of HIV-1 Infection: A Novel Concept Using Long-Acting Anti-Retroviral Drugs for Treating HIV-1

Marc Nischang,
Roger Sutmuller,
Gustavo Gers-Huber,
Annette Audigé,
Duo Li,
Mary-Aude Rochat,
Stefan Baenziger,
Ursula Hofer,
Erika Schlaepfer,
Stephan Regenass

Published: June 13, 2012
https://doi.org/10.1371/journal.pone.0038853

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

HIV
Is the Subject Area "HIV" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
HIV infections
Is the Subject Area "HIV infections" applicable to this article?

Thanks for your feedback.
Antiretroviral therapy
Is the Subject Area "Antiretroviral therapy" applicable to this article?

Thanks for your feedback.
Protease inhibitor therapy
Is the Subject Area "Protease inhibitor therapy" applicable to this article?

Thanks for your feedback.
Drug therapy
Is the Subject Area "Drug therapy" applicable to this article?

Thanks for your feedback.
Food
Is the Subject Area "Food" applicable to this article?

Thanks for your feedback.
Blood plasma
Is the Subject Area "Blood plasma" applicable to this article?

Thanks for your feedback.