Phosphorylation of Serine 248 of C/EBPα Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency

Marie S. Hasemann; Mikkel B. Schuster; Anne-Katrine Frank; Kim Theilgaard-Mönch; Thomas Å. Pedersen; Claus Nerlov; Bo T. Porse

doi:10.1371/journal.pone.0038841

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Research Article

Phosphorylation of Serine 248 of C/EBPα Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency

Marie S. Hasemann ,

Contributed equally to this work with: Marie S. Hasemann, Mikkel B. Schuster

Affiliations The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark, Danish Stem Cell Centre (DanStem) Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Mikkel B. Schuster ,

Contributed equally to this work with: Marie S. Hasemann, Mikkel B. Schuster

Affiliations The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark, Danish Stem Cell Centre (DanStem) Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Anne-Katrine Frank,

Affiliations The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark, Danish Stem Cell Centre (DanStem) Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Kim Theilgaard-Mönch,

Affiliations The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark, Deptartment of Hematology, Skanes University Hospital, University of Lund, Lund, Sweden
⨯
Thomas Å. Pedersen,

Current address: Novo Nordisk A/S, Måløv, Denmark

Affiliation European Molecular Biology Laboratory (EMBL) Mouse Biology Unit, Monterotondo, Italy
⨯
Claus Nerlov,

Affiliations European Molecular Biology Laboratory (EMBL) Mouse Biology Unit, Monterotondo, Italy, Medical Research Council (MRC) Center for Regenerative Medicine, Institute for Stem Cell Research, University of Edinburg, Edinburg, United Kingdom
⨯
Bo T. Porse

* E-mail: bo.porse@finsenlab.dk

Affiliations The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark, Danish Stem Cell Centre (DanStem) Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
⨯

Phosphorylation of Serine 248 of C/EBPα Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency

Marie S. Hasemann,
Mikkel B. Schuster,
Anne-Katrine Frank,
Kim Theilgaard-Mönch,
Thomas Å. Pedersen,
Claus Nerlov,
Bo T. Porse

Published: June 8, 2012
https://doi.org/10.1371/journal.pone.0038841

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Cell differentiation
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Phosphorylation
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Spleen
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Serine
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