Liver Progenitor Cell Line HepaRG Differentiated in a Bioartificial Liver Effectively Supplies Liver Support to Rats with Acute Liver Failure

Geert A. A. Nibourg; Robert A. F. M. Chamuleau; Tessa V. van der Hoeven; Martinus A. W. Maas; An F. C. Ruiter; Wouter H. Lamers; Ronald P. J. Oude Elferink; Thomas M. van Gulik; Ruurdtje Hoekstra

doi:10.1371/journal.pone.0038778

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Peer-reviewed

Research Article

Liver Progenitor Cell Line HepaRG Differentiated in a Bioartificial Liver Effectively Supplies Liver Support to Rats with Acute Liver Failure

Geert A. A. Nibourg,

Affiliations Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Surgery (Surgical Laboratory), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Robert A. F. M. Chamuleau,

Affiliation Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Tessa V. van der Hoeven,

Affiliations Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Surgery (Surgical Laboratory), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Martinus A. W. Maas,

Affiliation Department of Surgery (Surgical Laboratory), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
An F. C. Ruiter,

Affiliation Department of Clinical Chemistry, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Wouter H. Lamers,

Affiliation Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Ronald P. J. Oude Elferink,

Affiliation Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Thomas M. van Gulik,

Affiliation Department of Surgery (Surgical Laboratory), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Ruurdtje Hoekstra

* E-mail: r.hoekstra@amc.uva.nl

Affiliations Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Surgery (Surgical Laboratory), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯

Liver Progenitor Cell Line HepaRG Differentiated in a Bioartificial Liver Effectively Supplies Liver Support to Rats with Acute Liver Failure

Geert A. A. Nibourg,
Robert A. F. M. Chamuleau,
Tessa V. van der Hoeven,
Martinus A. W. Maas,
An F. C. Ruiter,
Wouter H. Lamers,
Ronald P. J. Oude Elferink,
Thomas M. van Gulik,
Ruurdtje Hoekstra

Published: June 18, 2012
https://doi.org/10.1371/journal.pone.0038778

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