Etiologic Diagnosis of Lower Respiratory Tract Bacterial Infections Using Sputum Samples and Quantitative Loop-Mediated Isothermal Amplification

• Yu Kang ,

  Contributed equally to this work with: Yu Kang, Rui Deng, Can Wang, Tao Deng

  Affiliations Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing, People’s Republic of China, Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Science, Beijing, People’s Republic of China

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• Rui Deng ,

  Contributed equally to this work with: Yu Kang, Rui Deng, Can Wang, Tao Deng

  Affiliation Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing, People’s Republic of China

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• Can Wang ,

  Contributed equally to this work with: Yu Kang, Rui Deng, Can Wang, Tao Deng

  Affiliation Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People’s Republic of China

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• Tao Deng ,

  Contributed equally to this work with: Yu Kang, Rui Deng, Can Wang, Tao Deng

  Affiliation Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People’s Republic of China

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• Peichao Peng,

  Affiliation School of Mathematical Sciences and Center for Theoretical Biology, Peking University, Beijing, People’s Republic of China

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• Xiaoxing Cheng,

  Affiliation School of Mathematical Sciences and Center for Theoretical Biology, Peking University, Beijing, People’s Republic of China

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• Guoqing Wang,

  Affiliation Department of Assay Development, Capitalbio Corporation, Beijing, People’s Republic of China

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• Minping Qian,

  Affiliation School of Mathematical Sciences and Center for Theoretical Biology, Peking University, Beijing, People’s Republic of China

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• Huafang Gao,

  Affiliation Department of Assay Development, Capitalbio Corporation, Beijing, People’s Republic of China

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• Bei Han,

  Affiliation Department of Assay Development, Capitalbio Corporation, Beijing, People’s Republic of China

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• Yusheng Chen,

  Affiliation Department of Respiratory Medicine, Fujian Provincial Hospital, Fuzhou, People’s Republic of China

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• Yinghui Hu,

  Affiliation Department of Respiratory Medicine, Beijing Children’s Hospital Affiliated to Capital Medical University, Beijing, People’s Republic of China

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• Rong Geng,

  Affiliation Department of Emergency Medicine, Beijing Children’s Hospital affiliated to Capital Medical University, Beijing, People’s Republic of China

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• Chengping Hu,

  Affiliation Department of Respiratory Medicine, Xiangya Hospital of Central South University, Changsha, People’s Republic of China

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• Wei Zhang,

  Affiliation Department of Respiratory Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China

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• Jingping Yang,

  Affiliation Department of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of the Inner Mongolia Medical College, Baotou, People’s Republic of China

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• Huanying Wan,

  Affiliation Department of Respiratory Medicine, Ruijin Hospital Affiliated to Shanghai Jiaotong University, Shanghai, People’s Republic of China

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• Qin Yu,

  Affiliation Department of Respiratory Medicine, The First Hospital of Lan Zhou University, Lanzhou, People’s Republic of China

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• Liping Wei,

  Affiliation Department of Respiratory Medicine, The Third Affiliated Hospital of Guangzhou Medical College, Guangzhou, People’s Republic of China

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• Jiashu Li,

  Affiliation Department of Respiratory Medicine, Lianyungang First People’s Hospital affiliated to Xuzhou Medical College, Lianyungang, People’s Republic of China

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• Guizhen Tian,

  Affiliation Department of Respiratory Medicine, NO.263 Clinical Section of the Military General Hospital of Beijing, Beijing, People’s Republic of China

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• Qiuyue Wang,

  Affiliation Institute of Respiratory Disease, The First Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China

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• Ke Hu,

  Affiliation Department of Respiratory Medicine, Renmin Hospital of Wuhan University, Wuhan, People’s Republic of China

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• Siqin Wang,

  Affiliation Department of Respiratory Medicine, Henan Province People’ Hospital, Zhengzhou, People’s Republic of China

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• Ruiqin Wang,

  Affiliation Department of Respiratory Medicine, The First Affiliated Hospital of Tsinghua University, Beijing, People’s Republic of China

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• Juan Du,

  Affiliation Department of Respiratory Medicine, The Affiliated Hospital of GuiYang Medical College, Guiyang, People’s Republic of China

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• Bei He,

  Affiliation Department of Respiratory Medicine, Peking University Third Hospital, Beijing, People’s Republic of China

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• Jianjun Ma,

  Affiliation Department of Respiratory Medicine, Lanzhou Pulmonary Hospital, Lanzhou, People’s Republic of China

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• Xiaoning Zhong,

  Affiliation Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China

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• Lan Mu,

  Affiliation Department of Respiratory Medicine, Peking University Space Central Hospital, Beijing, People’s Republic of China

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• Shaoxi Cai,

  Affiliation Department of Respiratory Medicine, Nanfang Hospital Affiliated to Southern Medical University, Guangzhou, People’s Republic of China

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• Xiangdong Zhu,

  Affiliation Section of Pulmonary and Critical Care Medicine (MC 6076), Department of Medicine, University of Chicago, Chicago, Illinois, United States of America

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• Wanli Xing,

  Affiliations Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People’s Republic of China, Department of Assay Development, Capitalbio Corporation, Beijing, People’s Republic of China

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• Jun Yu,

  Affiliation Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Science, Beijing, People’s Republic of China

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• Minghua Deng ,

  * E-mail: dengmh@pku.edu.cn (MD); zcgao@bjmu.edu.cn (ZG)

  ¶To whom correspondence about mathematic model and statistics should be addressed.

  Affiliation School of Mathematical Sciences and Center for Theoretical Biology, Peking University, Beijing, People’s Republic of China

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•  [ ... ],
• Zhancheng Gao

  * E-mail: dengmh@pku.edu.cn (MD); zcgao@bjmu.edu.cn (ZG)

  Affiliation Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing, People’s Republic of China

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