Coaggregation of RNA-Binding Proteins in a Model of TDP-43 Proteinopathy with Selective RGG Motif Methylation and a Role for RRM1 Ubiquitination

Eric B. Dammer; Claudia Fallini; Yair M. Gozal; Duc M. Duong; Wilfried Rossoll; Ping Xu; James J. Lah; Allan I. Levey; Junmin Peng; Gary J. Bassell; Nicholas T. Seyfried

doi:10.1371/journal.pone.0038658

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Research Article

Coaggregation of RNA-Binding Proteins in a Model of TDP-43 Proteinopathy with Selective RGG Motif Methylation and a Role for RRM1 Ubiquitination

Eric B. Dammer,

Affiliations Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Claudia Fallini,

Affiliations Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Yair M. Gozal,

Affiliation Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Duc M. Duong,

Affiliations Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Wilfried Rossoll,

Affiliations Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Ping Xu,

Current address: State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing, China

Affiliation Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
James J. Lah,

Affiliations Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Allan I. Levey,

Affiliations Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Junmin Peng,

Current address: St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

Affiliations Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Gary J. Bassell,

Affiliations Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Nicholas T. Seyfried

* E-mail: nseyfri@emory.edu

Affiliations Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯

Coaggregation of RNA-Binding Proteins in a Model of TDP-43 Proteinopathy with Selective RGG Motif Methylation and a Role for RRM1 Ubiquitination

Eric B. Dammer,
Claudia Fallini,
Yair M. Gozal,
Duc M. Duong,
Wilfried Rossoll,
Ping Xu,
James J. Lah,
Allan I. Levey,
Junmin Peng,
Gary J. Bassell

Published: June 21, 2012
https://doi.org/10.1371/journal.pone.0038658

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15 Feb 2013
19:54 GMT
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Need for primary citation of this research Posted by edammer on 15 Feb 2013 at 19:54 GMT

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